The injection solution contains local anesthetic (lidocaine or procaine), dextrose, adenosine monophosphate, and vitamin B12. These ingredients help trigger a healing response which stimulates blood flow and connective tissue production, thereby improving overall stability of the joint.
Treatment intervals vary depending on the specific problem and severity of the area being treated, as well as the protocol of the practitioner. Typical intervals between treatments are every two to six weeks, with an average interval of once a month, for a total of four to six treatments. However this can vary and may be more frequent, or take longer, depending on the condition being treated.
You may experience a few days of soreness in the area following treatment. This is related to the healing reaction being stimulated. After this initial recovery period, about 50% of patients report improvements in overall pain or mobility after only one treatment. For other patients, it may take 2 – 3 treatments for notable improvements to occur.
Corticosteroid (often referred to as “cortisone”) injections can be very effective for suppressing inflammation and related arthritis symptoms. Unfortunately, cortisone does not fix the underlying problems which are usually related to joint degeneration and/or joint instability.
In contrast, prolotherapy is considered a regenerative therapy – it can help strengthen tendons, ligaments and improve the overall stability of the joint in question. After several treatments, it has been shown to significantly improve symptoms related to arthritis and joint instability.